KEGG   REACTION: R02875
Entry
R02875                      Reaction                               
Name
squalene hydro-lyase (tetrahymanol forming)
Definition
Squalene + H2O <=> Tetrahymanol
Equation
Comment
multi-step reaction
Reaction class
RC01579  C00751_C06083
Enzyme
Pathway
rn00909  Sesquiterpenoid and triterpenoid biosynthesis
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 4. Lyase reactions
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.123
     R02875  Squalene + H2O <=> Tetrahymanol
Orthology
K26054  tetrahymanol synthase [EC:4.2.1.123]
Reference
1  [PMID:1892870]
  Authors
Saar J, Kader JC, Poralla K, Ourisson G
  Title
Purification and some properties of the squalene-tetrahymanol cyclase from Tetrahymena thermophila.
  Journal
Biochim Biophys Acta 1075:93-101 (1991)
DOI:10.1016/0304-4165(91)90080-Z
Other DBs
RHEA: 30678

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